Thought I'd update my input on this. I got back into gigging bands about 18 months ago and having back issues, after much trial and error, this is the rig i use;
For small rooms- Eden WTX260 260 watt @ 4 ohms (discontinued but now a Nemesis head) with an Avatar 2x10 Neo cab which handles 500 watts @ 4 ohms
Bigger rooms-Eden E300T 300 watt @ 4 or 8 ohms all tube monster head and same Avatar 2x10 Neo.
The WTX260 has plenty of beef for a small room with great tone and weighs 4.3 lbs and fits in the pocket of the gig bag!
The E300T weighs just 42 lbs probably due to toroidal transformers.
Avatar claims their Neo 2x10 also weighs 42 lbs but I think its closer to 48 according to my back LOL!
I do load ins in three relatively easy trips with the tube head and two relatively easy trips with the micro head.
If i can figure out how to keep my wife from killing me, I'm gonna upgrade to an Earcandy 2x10 Neo at some point with the Cabbiecab luggage system.
Why is it that women who know NOTHING of gear can instantly figure out you upgraded even if something mostly looks the same? LMAO!