I've played a couple of basses with the same bridge before/after adjusters were added, but only briefly on either side. IMO, yes, it changes the sound, a little, but not for the better or worse - just different. And not enough to convince me it isn't just in my head, either. Like Ken, I think if you're going to put adjusters in a bridge, get the biggest easiest-to-grab ones you can find - they all mess up the look of a nice bridge anyway.
Personally, I don't get enough use out of adjusters to make them worthwhile. I think they look funny, and I'd rather just keep two bridges (if needed) - if the climate in a particular area changes enough over the seasons to really
need adjusters, you probably need two soundposts anyway - might as well swap them both and clean your fingerboard at the same time...
