"Speakon" Cable: A Big Difference, or Not?

[Ronson Hall]

I've been discussing Eden amps & cabinets with Tim, and strolling through various music shops to compare the gear. I've noticed that, since I acquired my Eden Traveler Plus amp, almost every amp worth its salt has the option of a 1/4" out, or a "Speakon" out installed (cabs as well).

I've yet to use a Speakon cable. Are there pros and cons with it? Does one lose anything in terms of signal at all?